Cirrhosis

Categorizing Cirrhosis

Mortality

• Much higher in those with cirrhosis
  • 26.4% per two-year interval in those with cirrhosis versus 8.4% in propensity matched controls
• Significant differences when comparing compensated and decompensated cirrhosis
  • Risk of death:
    • Compensated: 4.7 times higher than the general population
    • Decompensated: 9.7 times higher than the general population
  • Life expectancy:
    • Compensated: 10-13 years
    • Decompensated: as little as 2 years

Financial Burden

• Continuing to rise due to cirrhosis and associated complications requiring hospitalization
  • Estimated direct and indirect costs to be in the billions
  • As hospitalizations go up, so does the cost burden on the healthcare system
• Extended length of stay, medications, and need for emergent procedures all increase cost in this patient population
• Chronic liver disease patients have also been shown to have
  • Longer admissions
  • More readmissions
  • Less access to care than other disease states