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Lesson 8 of8
In Progress

Overview of Evidence

Riszel February 18, 2022
Author, Year Design or Sample Size Intervention & Comparison Outcome
Kuang, 2016 Retrospective (n=398) BB naïve patients vs patients on chronic BB therapy -BB naïve patients achieved successful rate control at higher rates
Martindale, 2015 Systematic

review (n=92)

Diltiazem vs Metropolol -Diltiazem is more effective at rapidly controlling ventricular rates
Fromm, 2015 Prospective,

randomized,

double blind

(n=52)

Diltiazem 0.25 mg/kg (max 30mg) vs Metropolol 0.15 mg/kg (max 10mg) -Diltiazem decreased heart rate more rapidly and substantially within first 30min
Scheuermeyer,

2013

Retrospective (n=259) CCB (Diltiazem or Verapamil) vs BB (Metropolol or Atenolol) No difference in admission rates, length of stay, adverse events, and 7 or 30-day ED revisits
Demircan,

2005

Prospective,

randomized

(n=40)

Diltiazem 0.25mg/kg (max 25mg) Metoprolol 0.15mg/kg (max 10mg) -Successful rate control was similar at 20 minutes