Post-Quiz: DVT Prophylaxis

A 62-year-old male patient, Mr. Smith, is admitted to the hospital for elective total hip replacement surgery due to osteoarthritis. He has a medical history of hypertension, type 2 diabetes mellitus, and a prior DVT episode following a long-haul flight five years ago. His current medications include metformin, lisinopril, and atorvastatin. Mr. Smith’s BMI is 32, and he reports being a non-smoker. In the preoperative evaluation, which of the following is the most appropriate DVT prophylaxis strategy for Mr. Smith?

Which of the following is NOT a recommended pharmacological intervention for DVT prophylaxis in a patient undergoing abdominal surgery?

In a patient at high risk for DVT but with a contraindication to pharmacological prophylaxis, which of the following is the best alternative intervention?

A 65-year-old female with a recent history of immobility due to a leg fracture is being considered for DVT prophylaxis. Which of the following best describes the mechanism by which immobility increases the risk of DVT?

Which of the following medications is associated with an increased risk of DVT due to its hypercoagulable effect?

A 70-year-old male postoperative patient on DVT prophylaxis with unfractionated heparin develops thrombocytopenia. What condition should be strongly considered?

Mr. Smith, a 78-year-old male weighing 68 kg, is admitted to the hospital with worsening chronic heart failure. His past medical history includes hypertension, type 2 diabetes mellitus, and chronic kidney disease. Current medications include lisinopril, metformin, and a beta-blocker. A recent laboratory report shows serum creatinine at 2.5 mg/dL. Considering his hospitalization for a medical illness and risk factors, the team is contemplating DVT prophylaxis with enoxaparin. Based on his renal function, how should enoxaparin be dosed?